Skip to main content
Health & Medicine

Governing the digital determinants of health for children and young people: a global public health imperative.

| Source: Lancet (London, England)

The digital determinants of health are the structural conditions through which digital infrastructures, business models, and design choices shape health outcomes. Yet these determinants remain largely outside public health policy and remain fragmented across regulatory sectors. Rather than regulating individual technologies in isolation, governance should ensure that digital systems and environments advance population health and reduce inequities. A public health approach shifts attention from i

The digital determinants of health are the structural conditions through which digital infrastructures, business models, and design choices shape health outcomes. Yet these determinants remain largely outside public health policy and remain fragmented across regulatory sectors. Rather than regulating individual technologies in isolation, governance should ensure that digital systems and environments advance population health and reduce inequities. A public health approach shifts attention from individual responsibility-and the tendency to blame users-towards the governance of the structural features that produce health risks and inequities. We identify four governance domains for the digital determinants of health: infrastructure and access, platform design and commercial practices, data governance and surveillance, and institutional accountability and rights. Effectively governing these domains requires intersectoral strategies that tackle problematic concentrations of political and economic power. We argue that the governance of the digital determinants of health should be recognised as a core public health function, with the health of children and young people as a priority and entry point and precaution as a guiding governance principle.

Read the original source →

Related Stories

Health & Medicine

The honey bee stinger: An unusual pump with collapsible double pistons.

Most stinging animals deliver venom by contracting muscles around a venom reservoir, but honey bees employ a fundamentally different strategy. The stingers of worker bees have the unique ability to autotomize, separating from the body, to continue to sting independently. Despite more than a century of anatomical descriptions, the mechanics of venom pumping have remained unresolved due to the challenges of observing them in action. We recorded high-speed videos of active, autotomized stingers, co

Continue reading
Health & Medicine

Chronic cigarette smoke exposure induces distinct stem cell states driving genetic driver-specific non-small cell lung cancer subtypes.

Cigarette smoke-induced chronic inflammation (CI) potentiates development of non-small cell lung cancer (NSCLC) by mediating genetic and epigenetic events. Using normal lung organoids (LOs), we define how chronic cigarette smoke condensate (CSC) exposure drives two separate stem cell populations to evolve premalignant states harboring progressive epigenetic and linked transcriptomic abnormalities in the absence of major driver mutations. These dynamics facilitate evolution of an immune evasive s

Continue reading
Health & Medicine

Cell identity competes with surface tension to determine stromal organization in tumor spheroids beyond the CAF shell paradigm.

Cancer-associated fibroblasts (CAFs) are often found forming a peripheral stromal barrier around tumors. Here, this paradigm is challenged using microfabricated 3D cancer-CAF spheroid models combined with quantitative magnetic force tensiometry. A surface tension atlas is established for eight cancer cell lines, three CAF populations, and heterotypic tumor-CAF assemblies, spanning nearly two orders of magnitude. Surface tension is first shown to govern spheroid morphology and modulate drug respo

Continue reading
Health & Medicine

Sexual dimorphism in epidermal stem cell dynamics.

The epidermis is a stratified epithelium comprising proliferative basal cells and differentiated suprabasal cells that are continuously renewed throughout life. Conflicting theories have been proposed regarding the heterogeneity of the basal cell layer, with some studies proposing that all proliferative cells have self-renewal potential during homeostasis 1-5 . Meanwhile, others posit a model in which stem cell differentiation occurs through an intermediate transit-amplifying-like progenitor sta

Continue reading
Health & Medicine

Engineered TYK2 dependence enables myeloid-selective IL-10 receptor agonism.

Interleukin-10 (IL-10) is a central anti-inflammatory cytokine that suppresses immune responses in myeloid cells but can also activate T cells, limiting its therapeutic use in chronic inflammatory diseases owing to narrow efficacy windows and dose-limiting toxicities 1-5 . Here we show that myeloid and T cells differ in their dependence on JAK-family kinase pairing for IL-10 signalling and function. We took advantage of this differential kinase dependence to engineer a tetravalent nanobody-based

Continue reading